The project: By combining theory, experiments, and engineering – as well as shifting our thinking from a genome centric to a metabolism centric point of view – David seeks to understand how cells use networks of macromolecules to learn, adapt, and improvise.
The motivation: “Looking to biology for inspiration, to physics for rigour, and to technology for applications has proved to be a very fruitful path to progress. One of the main goals of my research is to understand how biological systems manage to organise themselves such that the natural unfolding of their dynamics, as dictated by the laws of physics, provides computations useful for prediction, adaptation, and control.”
The project: Investigating the controllability of stochastic switching in magnetic tunnel junctions, the team are developing protocols to drive these memory devices as ultra-high-speed, high-quality hardware-based true random number generators.
The motivation: “Modelling probabilistic processes on computers designed for deterministic calculations is highly inefficient, yet the behaviour of the underlying devices is rich with randomness — all we need to do is harness it. Our team is motivated to build a high performance, practical product for true random number generation at-large-scale, simply by getting creative with how we drive known devices and commercial hardware. Coupled with DSV’s established venture building approach, the Nature Computes Better philosophy fits this ambition perfectly.”
The project: Juliane and Kimia are aiming to engineer miniature vehicles that respond to external stimuli, each exhibiting specific behaviours that correspond to symbolic representations.
The motivation: “Beyond simply drawing inspiration from nature to engineer novel technologies, we need to take a step further and begin co-engineering with it.”
The project: Kirsty is aiming to unravel the basis of natural computation in single-celled organisms through an interdisciplinary approach combining bioimaging, live-cell experiments, and modelling, to study how single cells compute using physical attributes of its body and the environment.
The motivation: “We can learn so much from how living systems compute at all scales, and there are distinct challenges of ‘being alive’ that make these systems so much more robust and flexible than non-living architectures.”
The project: As large language model workloads scale, their compute requirements are outstripping the capabilities of the substrates on which they run. Phillip asks if architectures capable of natively representing probability distributions could serve as radically more efficient computing substrates for AI workloads.
The motivation: “Computation plays an important role in all aspects of society. There is currently a missed opportunity to use an understanding of the physical world to design efficient computing systems that interact with nature.”
The project: Glass is a promising substrate for next-generation optical computing paradigms – Martin is aiming to address a critical aspect of technology deployment, which is the ability to manufacture at scale.
The motivation: “There is an urgent need for technology advancement in this area and there are many impressive ideas about how optical methods can be used to improve future computing technology.”
The project: Danyal is combining biologically-inspired neural networks with neuromorphic hardware to test out the idea that delays between spatially embedded neurons, rather than slowing down computation, endows networks with significantly elevated computational capacities at a relatively cheap cost.
The motivation: “Computation in the brain is much more complex than just tuning synaptic weights. I think we can learn a huge amount from where (in space) and when (through time) computation happens in the brain, and translate these learned principles to new efficient artificial intelligence architectures.”
The project: Viv and Susan will develop natural computational models taking into account what we can build in the lab, and the natural properties of photons, including that they aren’t conserved (massless bosons). Such a model will include photon loss – and gain – as features, not bugs.
The motivation: “Instead of trying to force photons into computational models designed for matter (fermions), building models based on their intrinsic properties should give us the optimal ways to use photonics for computation, because we won’t be wasting resources to make the system do things that are hard/expensive.”
The project: Relating thought to pyramidal two-point cells, Adeel is aiming to develop a new form of AI chip that is economical and, when guided by its owners’ needs and values, will empower individuals to make more informed judgements.
The motivation: “There is convergent validity among recent cellular neurobiological discoveries, high-resolution modelling, and biologically plausible simulations that pyramidal two-point cells operate in different modes. These modes include slow-wave sleep, the typical wakeful state (common sense), and imaginative thought. This suggests that cellular mechanisms could be embodied in machines to enable cognitive capabilities that are effective and economical.”
Suraj Bramhavar, ARIA Programme Director